L’anticorps Souris Monoclonal anti-Coagulation Factor IX a été validé pour EIA. Il convient pour détecter Coagulation Factor IX dans des échantillons de Humain.
N° du produit ABIN452591
Aperçu rapide pour Coagulation Factor IX anticorps (ABIN452591)
F9
Reactivité: Humain
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Reconstitution
Restore with Double distillated water to a final concentration of 1.0 mg/mL.
Buffer
0.01 M PBS, pH 7.2 without preservatives.
Agent conservateur
Without preservative
Stock
-20 °C
Stockage commentaire
Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Date de péremption
12 months
Antigène
Coagulation Factor IX (F9)
Sujet
Factor IX circulates in the blood as an inactive zymogen at the normal concentration of approximately 3 μg/mL. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca2+ ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X linked disorder, also called hemophilia B or Christmas disease. The disease affects approximately 1 in 50,000 of the population (almost exclusively males).Synonyms: Christmas factor, PTC, Plasma thromboplastin component